Rich,
I made deer rifles out of a .375 H&H as well as a .458 Winchester. For the .375 I used the Speer 235 grain bullet and 64 grains of IMR 4064 @ 2300 fps. The .458 load is Speer 405 grain flat nose and 65 grains of IMR 4064 @ 1800 fps. Both very mild loads and you could shoot them all day plus they didn't bruse the meat at those velocities. I took them from an article by Finn Aaggard. Have you thought of paper patching a 40 cal 180 grain lead bullet? I think you would have to use WW 231 or Bullseye to get the velocity low enough to regulate.
Harry
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