Both my dogs have been vaccinated against rattlesnake toxin. FYI it is a two step process. A primary is followed by a booster 30 days later then they get an annual booster. It is said that there can be an adverse reaction but I haven’t seen any.
My local vet had no experience with it but she got a box of ten vials from the university vet school which I paid $125 for the whole box. She keeps the box refrigerated and vaccinates the dogs without further cost when they need the shots . This is a lot less expensive than having a dog bit then rushing the dog to the vet and then all the steroids or whatever they do to combat the toxin . Plus you get some peace of mind.
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