John, we have had to deal with various tumors on GSDs and American Bulldogs. Since the only options were low odds that they would last through surgery with no guarantees that they'd live more than a few months, we opted to have them put down. Having a dog active on 3 legs is a better option than having a dog knocked down due to radiation or chemo knowing full well the dog does not feel good nor understands why. If amputation is the only option and they could guarantee they removed all the cancer, then I'd opt for amputation. It's a very personal decision. Prayers for wisdom.
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