Randy,
I can't make any recommendations on what road construction you will encounter. I think the upper route (I 80) in Pa would be a bigger highway and maybe less congested because you're further from Pittsburg.
I thought the lower route would have some tolls, but after plugging it into Google Maps from Columbus to Meshoppen, the route it suggests doesn't show any tolls.
I like traveling 80 when I'm up that way, (big rolling mountains and scenery) but I rarely do since I'm in the lower half of the state.
JMO,
Stan Hoover
PS. I personally prefer the scenery from the top down