There are all sorts of opinions but the only way you will really find out for yourself is to pattern the gun with different loads at different distances.
All of my Parker 16's pattern well with 6's and with full choke are effective between 40-60 yards provided I do my job. Usually when the target is missed the problem is at the rear of the gun.
For #5 shot in a 16, the pattern gets raggedy, so I favor 6's and 7 1/2's in a 16. #5 shot is better put through a larger bore gun when you need long distance penetration.
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